Cargando…

Paeoniflorin Improved Constipation in the Loperamide-Induced Rat Model via TGR5/TRPA1 Signaling-Mediated 5-Hydroxytryptamine Secretion

Slow transit constipation (STC) is a common type of constipation with a high incidence rate and a large number of patients. We aimed to investigate the therapeutic effects and potential mechanism of paeoniflorin (PAE) on loperamide-induced Sprague Dawley (SD) rat constipation models. Rats with loper...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhan, Yu, Wen, Yong, Zhang, Liang-liang, Shen, Xu-long, Chen, Xiao-hui, Wu, Xiao-hai, Tang, Xue-gui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674056/ https://www.ncbi.nlm.nih.gov/pubmed/34925531 http://dx.doi.org/10.1155/2021/6076293

Ejemplares similares

Effects of probiotics on loperamide-induced constipation in rats
por: Inatomi, Takio, et al.
Publicado: (2021)

Luteolin ameliorates loperamide-induced functional constipation in mice
por: Wang, Yujin, et al.
Publicado: (2023)

5- Hydroxytryptamine
por: Giarman, Nicholas J.
Publicado: (1958)

The Mechanism of Secretion and Metabolism of Gut-Derived 5-Hydroxytryptamine
por: Liu, Ning, et al.
Publicado: (2021)

Effect of Colic Vein Ligature in Rats with Loperamide-Induced Constipation
por: Neri, Flavia, et al.
Publicado: (2012)

Effect of dual-type oligosaccharides on constipation in loperamide-treated rats
por: Han, Sung Hee, et al.
Publicado: (2016)

The potential of Quercetin to protect against loperamide‐induced constipation in rats
por: Liu, Wenhui, et al.
Publicado: (2021)

Integrated metagenomics and targeted-metabolomics analysis of the effects of phenylalanine on loperamide-induced constipation in rats
por: Yang, Chuanli, et al.
Publicado: (2022)

Laxative effects of fermented rice extract in rats with loperamide-induced constipation
por: CHOI, JAE-SUK, et al.
Publicado: (2014)

Metabolomics approach to serum biomarker for loperamide-induced constipation in SD rats
por: Kim, Ji-Eun, et al.
Publicado: (2014)

Prevention of Loperamide-Induced Constipation in Mice and Alteration of 5-Hydroxytryotamine Signaling by Ligilactobacillus salivarius Li01
por: Qiu, Bo, et al.
Publicado: (2022)

STORAGE OF 5-HYDROXYTRYPTAMINE IN MEGAKARYOCYTES
por: Tranzer, J. P., et al.
Publicado: (1972)

Characterization the response of Korl:ICR mice to loperamide induced constipation
por: Kim, Ji Eun, et al.
Publicado: (2016)

Buzhongyiqi Decoction Protects Against Loperamide-Induced Constipation by Regulating the Arachidonic Acid Pathway in Rats
por: Ju, Wan-Jun, et al.
Publicado: (2020)

The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats
por: Wintola, Olubunmi A, et al.
Publicado: (2010)

Cactus (Opuntia humifusa) water extract ameliorates loperamide-induced constipation in rats
por: Han, Sung Hee, et al.
Publicado: (2017)

Amylase-Producing Maltooligosaccharide Provides Potential Relief in Rats with Loperamide-Induced Constipation
por: Jang, Eun Yeong, et al.
Publicado: (2020)

TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
por: Harach, Taoufiq, et al.
Publicado: (2012)

Comparative Study of Constipation Exacerbation by Potassium Binders Using a Loperamide-Induced Constipation Model
por: Narita, Yuki, et al.
Publicado: (2020)

Gut microbiota is involved in the alleviation of loperamide‐induced constipation by honey supplementation in mice
por: Li, Yuyuan, et al.
Publicado: (2020)

Aqueous Extracts of Herba Cistanche Promoted Intestinal Motility in Loperamide-Induced Constipation Rats by Ameliorating the Interstitial Cells of Cajal
por: Yan, Shuai, et al.
Publicado: (2017)

Serotonin in the rat prefrontal cortex controls the micturition reflex through 5‐hydroxytryptamine 2A and 5‐hydroxytryptamine 7 receptors
por: Chiba, Hiroki, et al.
Publicado: (2020)

Gastrointestinal Fermentable Polysaccharide Is Beneficial in Alleviating Loperamide-Induced Constipation in Mice
por: Liu, Buyu, et al.
Publicado: (2023)

The Relationship Between 5-Hydroxytryptamine and Its Metabolite Changes With Post-stroke Depression
por: Gu, Simeng, et al.
Publicado: (2022)

TGR5, Not Only a Metabolic Regulator
por: Guo, Cong, et al.
Publicado: (2016)

TGR5 Signaling in Hepatic Metabolic Health
por: Holter, Marlena M., et al.
Publicado: (2020)

Changes in the Gut Microbiome after Galacto-Oligosaccharide Administration in Loperamide-Induced Constipation
por: Kim, Min Guk, et al.
Publicado: (2020)

Polysaccharides from Holothuria leucospilota Relieve Loperamide-Induced Constipation Symptoms in Mice
por: Wang, Ziqi, et al.
Publicado: (2023)

Laxative effects of triple fermented barley extracts (FBe) on loperamide (LP)-induced constipation in rats
por: Lim, Jong-Min, et al.
Publicado: (2019)

Laxative Effects of Phlorotannins Derived from Ecklonia cava on Loperamide-Induced Constipation in SD Rats
por: Kim, Ji-Eun, et al.
Publicado: (2021)

Rifaximin Ameliorates Loperamide-Induced Constipation in Rats through the Regulation of Gut Microbiota and Serum Metabolites
por: Luo, Mei, et al.
Publicado: (2023)

5-Hydroxytryptamine Receptors and Tardive Dyskinesia in Schizophrenia
por: Pozhidaev, Ivan V., et al.
Publicado: (2020)

Uridine stimulate laxative effect in the loperamide-induced constipation of SD rats through regulation of the mAChRs signaling pathway and mucin secretion
por: Kim, Ji Eun, et al.
Publicado: (2017)

Quercetin promotes gastrointestinal motility and mucin secretion in loperamide-induced constipation of SD rats through regulation of the mAChRs downstream signal
por: Kim, Ji Eun, et al.
Publicado: (2018)

Mast cells are important regulator of acupoint sensitization via the secretion of tryptase, 5-hydroxytryptamine, and histamine
por: Ding, Ning, et al.
Publicado: (2018)

Serum 5-Hydroxytryptamine is Related to Psoriasis Severity in Patients with Comorbid Anxiety or Depression
por: SHEN, Minxue, et al.
Publicado: (2021)

Upregulation of 5-Hydroxytryptamine Receptor Signaling in Coronary Arteries after Organ Culture
por: Deng, Chun-Yu, et al.
Publicado: (2014)

The role of the 5-hydroxytryptamine pathway in reflux-induced esophageal mucosal injury in rats
por: Yang, Lingrong, et al.
Publicado: (2012)

Effects of Fermented Milk with Mixed Strains as a Probiotic on the Inhibition of Loperamide-Induced Constipation
por: Kim, Byoung-Kook, et al.
Publicado: (2017)

Synergistic Effect of Fermented Rice Extracts on the Probiotic and Laxative Properties of Yoghurt in Rats with Loperamide-Induced Constipation
por: Choi, Jae-Suk, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_r275gl49qfd5in45quh129ed37