A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus

Chikungunya virus (CHIKV) infection causes acute disease characterized by fever, rash and arthralgia, which progresses to severe and chronic arthritis in up to 50% of patients. Moreover, CHIKV infection can be fatal in infants or immunocompromised individuals and has no approved therapy or preventio...

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Detalles Bibliográficos
Autores principales: August, Allison, Attarwala, Husain Z., Himansu, Sunny, Kalidindi, Shiva, Lu, Sophia, Pajon, Rolando, Han, Shu, Lecerf, Jean-Michel, Tomassini, Joanne E., Hard, Marjie, Ptaszek, Leon M., Crowe, James E., Zaks, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674127/
https://www.ncbi.nlm.nih.gov/pubmed/34887572
http://dx.doi.org/10.1038/s41591-021-01573-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674127/
https://www.ncbi.nlm.nih.gov/pubmed/34887572
http://dx.doi.org/10.1038/s41591-021-01573-6

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