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Circulating PIK3CA mutation detection at diagnosis in non-metastatic inflammatory breast cancer patients

Inflammatory breast cancer (IBC) is an aggressive BC subtype with poor outcomes. A targetable somatic PIK3CA mutation is reported in 30% of IBC, allowing for treatment by PI3Kα-specific inhibitors, such as alpelisib. The aim of this study was to evaluate the detection rate of circulating PIK3CA muta...

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Detalles Bibliográficos
Autores principales: Allouchery, Violette, Perdrix, Anne, Calbrix, Céline, Berghian, Anca, Lequesne, Justine, Fontanilles, Maxime, Leheurteur, Marianne, Etancelin, Pascaline, Sarafan-Vasseur, Nasrin, Di Fiore, Frédéric, Clatot, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674263/
https://www.ncbi.nlm.nih.gov/pubmed/34911971
http://dx.doi.org/10.1038/s41598-021-02643-y