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Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway

Nonsteroidal anti-inflammatory drugs (NSAIDs), including salicylic acid (SA), target mammalian cyclooxygenases. In plants, SA is a defense hormone that regulates NON-EXPRESSOR OF PATHOGENESIS RELATED GENES 1 (NPR1), the master transcriptional regulator of immunity-related genes. We identify that the...

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Detalles Bibliográficos
Autores principales: Ishihama, Nobuaki, Choi, Seung-won, Noutoshi, Yoshiteru, Saska, Ivana, Asai, Shuta, Takizawa, Kaori, He, Sheng Yang, Osada, Hiroyuki, Shirasu, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674334/
https://www.ncbi.nlm.nih.gov/pubmed/34911942
http://dx.doi.org/10.1038/s41467-021-27489-w