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A functional spleen contributes to afucosylated IgG in humans

As a lymphoid organ, the spleen hosts a wide range of immune cell populations, which not only remove blood-borne antigens, but also generate and regulate antigen-specific immune responses. In particular, the splenic microenvironment has been demonstrated to play a prominent role in adaptive immune r...

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Detalles Bibliográficos
Autores principales: Wojcik, Iwona, Schmidt, David E., de Neef, Lisa A., Rab, Minke A. E., Meek, Bob, de Weerdt, Okke, Wuhrer, Manfred, van der Schoot, C. Ellen, Zwaginga, Jaap J., de Haas, Masja, Falck, David, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674363/
https://www.ncbi.nlm.nih.gov/pubmed/34911982
http://dx.doi.org/10.1038/s41598-021-03196-w