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A functional spleen contributes to afucosylated IgG in humans
As a lymphoid organ, the spleen hosts a wide range of immune cell populations, which not only remove blood-borne antigens, but also generate and regulate antigen-specific immune responses. In particular, the splenic microenvironment has been demonstrated to play a prominent role in adaptive immune r...
Autores principales: | Wojcik, Iwona, Schmidt, David E., de Neef, Lisa A., Rab, Minke A. E., Meek, Bob, de Weerdt, Okke, Wuhrer, Manfred, van der Schoot, C. Ellen, Zwaginga, Jaap J., de Haas, Masja, Falck, David, Vidarsson, Gestur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674363/ https://www.ncbi.nlm.nih.gov/pubmed/34911982 http://dx.doi.org/10.1038/s41598-021-03196-w |
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