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Generation of developmentally competent oocytes and fertile mice from parthenogenetic embryonic stem cells

Parthenogenetic embryos, created by activation and diploidization of oocytes, arrest at mid-gestation for defective paternal imprints, which impair placental development. Also, viable offspring has not been obtained without genetic manipulation from parthenogenetic embryonic stem cells (pESCs) deriv...

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Detalles Bibliográficos
Autores principales: Tian, Chenglei, Liu, Linlin, Zeng, Ming, Sheng, Xiaoyan, Heng, Dai, Wang, Lingling, Ye, Xiaoying, Keefe, David L., Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674391/
https://www.ncbi.nlm.nih.gov/pubmed/34845589
http://dx.doi.org/10.1007/s13238-021-00865-4