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Tilapia Piscidin 4 (TP4) Reprograms M1 Macrophages to M2 Phenotypes in Cell Models of Gardnerella vaginalis-Induced Vaginosis

Gardnerella vaginalis is associated with bacterial vaginosis (BV). The virulence factors produced by G. vaginalis are known to stimulate vaginal mucosal immune response, which is largely driven by activated macrophages. While Tilapia piscidin 4 (TP4), an antimicrobial peptide isolated from Nile tila...

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Detalles Bibliográficos
Autores principales: Liu, Chia-Wen, Su, Bor-Chyuan, Chen, Jyh-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674419/
https://www.ncbi.nlm.nih.gov/pubmed/34925343
http://dx.doi.org/10.3389/fimmu.2021.773013