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Two-step fitness selection for intra-host variations in SARS-CoV-2

Spontaneous mutations introduce uncertainty into coronavirus disease 2019 (COVID-19) control procedures and vaccine development. Here, we perform a spatiotemporal analysis on intra-host single-nucleotide variants (iSNVs) in 402 clinical samples from 170 affected individuals, which reveals an increas...

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Detalles Bibliográficos
Autores principales: Li, Jiarui, Du, Pengcheng, Yang, Lijiang, Zhang, Ju, Song, Chuan, Chen, Danying, Song, Yangzi, Ding, Nan, Hua, Mingxi, Han, Kai, Song, Rui, Xie, Wen, Chen, Zhihai, Wang, Xianbo, Liu, Jingyuan, Xu, Yanli, Gao, Guiju, Wang, Qi, Pu, Lin, Di, Lin, Li, Jie, Yue, Jinglin, Han, Junyan, Zhao, Xuesen, Yan, Yonghong, Yu, Fengting, Wu, Angela R., Zhang, Fujie, Gao, Yi Qin, Huang, Yanyi, Wang, Jianbin, Zeng, Hui, Chen, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674508/
https://www.ncbi.nlm.nih.gov/pubmed/34982968
http://dx.doi.org/10.1016/j.celrep.2021.110205