Pierce into Structural Changes of Interactions Between Mutated Spike Glycoproteins and ACE2 to Evaluate Its Potential Biological and Therapeutic Consequences

The structural consequences of ongoing mutations on the SARS-CoV-2 spike-protein remains to be fully elucidated. These mutations could change the binding affinity between the virus and its target cell. Moreover, obtaining new mutations would also change the therapeutic efficacy of the designed drug...

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Detalles Bibliográficos
Autores principales: Hashemi, Zahra Sadat, Zarei, Mahboubeh, Mubarak, Shaden M. H., Hessami, Anahita, Mard-Soltani, Maysam, Khalesi, Bahman, Zakeri, Alireza, Rahbar, Mohammad Reza, Jahangiri, Abolfazl, Pourzardosht, Navid, Khalili, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674523/
https://www.ncbi.nlm.nih.gov/pubmed/34931119
http://dx.doi.org/10.1007/s10989-021-10346-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674523/
https://www.ncbi.nlm.nih.gov/pubmed/34931119
http://dx.doi.org/10.1007/s10989-021-10346-1

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