Predictive value of mRNA expression and dynamic changes from immune related biomarkers in liquid biopsies before and after start of pembrolizumab in stage IV non-small cell lung cancer (NSCLC)

BACKGROUND: The aim of this study was to determine whether mRNA expressions and dynamic changes of immune-related genes before and after starting first-line treatment with the PD-1 inhibitor pembrolizumab in patients with NSCLC were of predictive value. METHODS: CD3, CD8, PD-1, PD-L1 and CTLA-4 mRNA...

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Detalles Bibliográficos
Autores principales: Brueckl, Natalie F., Wirtz, Ralph M., Reich, Fabian P. M., Veltrup, Elke, Zeitler, Gloria, Meyer, Christian, Wuerflein, Dieter, Ficker, Joachim H., Eidt, Sebastian, Brueckl, Wolfgang M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674604/
https://www.ncbi.nlm.nih.gov/pubmed/35004242
http://dx.doi.org/10.21037/tlcr-21-587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674604/
https://www.ncbi.nlm.nih.gov/pubmed/35004242
http://dx.doi.org/10.21037/tlcr-21-587

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