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Calcium Ions Aggravate Alzheimer’s Disease Through the Aberrant Activation of Neuronal Networks, Leading to Synaptic and Cognitive Deficits

Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by the production and deposition of β-amyloid protein (Aβ) and hyperphosphorylated tau, leading to the formation of β-amyloid plaques (APs) and neurofibrillary tangles (NFTs). Although calcium ions (Ca(2+)) promote the for...

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Detalles Bibliográficos
Autores principales: Guan, Pei-Pei, Cao, Long-Long, Yang, Yi, Wang, Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674839/
https://www.ncbi.nlm.nih.gov/pubmed/34924952
http://dx.doi.org/10.3389/fnmol.2021.757515