Cargando…
Calcium Ions Aggravate Alzheimer’s Disease Through the Aberrant Activation of Neuronal Networks, Leading to Synaptic and Cognitive Deficits
Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by the production and deposition of β-amyloid protein (Aβ) and hyperphosphorylated tau, leading to the formation of β-amyloid plaques (APs) and neurofibrillary tangles (NFTs). Although calcium ions (Ca(2+)) promote the for...
Autores principales: | Guan, Pei-Pei, Cao, Long-Long, Yang, Yi, Wang, Pu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674839/ https://www.ncbi.nlm.nih.gov/pubmed/34924952 http://dx.doi.org/10.3389/fnmol.2021.757515 |
Ejemplares similares
-
Elevating the Levels of Calcium Ions Exacerbate Alzheimer’s Disease via Inducing the Production and Aggregation of β-Amyloid Protein and Phosphorylated Tau
por: Guan, Pei-Pei, et al.
Publicado: (2021) -
Genetic Deficiency of p53 Leads to Structural, Functional, and Synaptic Deficits in Primary Somatosensory Cortical Neurons of Adult Mice
por: Kuang, Haixia, et al.
Publicado: (2022) -
Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1
por: Cao, Long-Long, et al.
Publicado: (2019) -
Signaling abnormality leading to excessive/aberrant synaptic plasticity in Alzheimer's disease
por: Kawabata, Shigeki
Publicado: (2022) -
Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease
por: Wei, Zhen, et al.
Publicado: (2016)