Long-Term Depression of Striatal DA Release Induced by mGluRs via Sustained Hyperactivity of Local Cholinergic Interneurons

The cellular mechanisms regulating dopamine (DA) release in the striatum have attracted much interest in recent years. By in vitro amperometric recordings in mouse striatal slices, we show that a brief (5 min) exposure to the metabotropic glutamate receptor agonist DHPG (50 μM) induces a profound de...

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Detalles Bibliográficos
Autores principales: Mercuri, Nicola B., Federici, Mauro, Rizzo, Francesca Romana, Maugeri, Lorenzo, D’Addario, Sebastian L., Ventura, Rossella, Berretta, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674918/
https://www.ncbi.nlm.nih.gov/pubmed/34924961
http://dx.doi.org/10.3389/fncel.2021.798464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674918/
https://www.ncbi.nlm.nih.gov/pubmed/34924961
http://dx.doi.org/10.3389/fncel.2021.798464

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