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Siponimod Inhibits the Formation of Meningeal Ectopic Lymphoid Tissue in Experimental Autoimmune Encephalomyelitis

BACKGROUND AND OBJECTIVES: To investigate whether the formation or retention of meningeal ectopic lymphoid tissue (mELT) can be inhibited by the sphingosine 1-phosphate receptor 1,5 modulator siponimod (BAF312) in a murine model of multiple sclerosis (MS). METHODS: A murine spontaneous chronic exper...

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Detalles Bibliográficos
Autores principales: Brand, Rosa Margareta, Diddens, Jolien, Friedrich, Verena, Pfaller, Monika, Radbruch, Helena, Hemmer, Bernhard, Steiger, Katja, Lehmann-Horn, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674936/
https://www.ncbi.nlm.nih.gov/pubmed/34911793
http://dx.doi.org/10.1212/NXI.0000000000001117