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NLRP3 inflammasome activation in gestational diabetes mellitus placentas is associated with hydrogen sulfide synthetase deficiency

The placenta may play a key role in the activation of inflammation and initiation of insulin resistance (IR) during gestational diabetes mellitus (GDM) pathogenesis. Interleukin (IL)-1β and IL-18, regulated by NLR family pyrin domain containing-3 (NLRP3) inflammasome, are important inflammatory cyto...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Tan, Qing-Ying, Xi, Fang-Fang, Ruan, Yun, Wang, Jing, Luo, Qiong, Dou, Xiao-Bing, Hu, Tian-Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674967/
https://www.ncbi.nlm.nih.gov/pubmed/34976136
http://dx.doi.org/10.3892/etm.2021.11017