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Controlled delivery of gold nanoparticle-coupled miRNA therapeutics via an injectable self-healing hydrogel

Differential expression of microRNAs (miRNAs) plays a role in many diseases, including cancer and cardiovascular diseases. Potentially, miRNAs could be targeted with miRNA-therapeutics. Sustained delivery of these therapeutics remains challenging. This study couples miR-mimics to PEG-peptide gold na...

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Detalles Bibliográficos
Autores principales: van der Ven, Casper F. T., Tibbitt, Mark W., Conde, João, van Mil, Alain, Hjortnaes, Jesper, Doevendans, Pieter A., Sluijter, Joost P. G., Aikawa, Elena, Langer, Robert S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675028/
https://www.ncbi.nlm.nih.gov/pubmed/34817483
http://dx.doi.org/10.1039/d1nr04973a