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Delineating the Aggregation-Prone Hotspot Regions (Peptides) in the Human Cu/Zn Superoxide Dismutase 1

[Image: see text] Amyotrophic lateral sclerosis (ALS) is a fatal, incurable neurodegenerative disease described by progressive degeneration of motor neurons. The most common familial form of ALS (fALS) has been associated with mutations in the Cu/Zn superoxide dismutase (SOD1) gene. Mutation-induced...

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Detalles Bibliográficos
Autores principales: Wahiduzzaman, Kumar, Vijay, Anjum, Farah, Shafie, Alaa, Elasbali, Abdelbaset Mohamed, Islam, Asimul, Ahmad, Faizan, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675042/
https://www.ncbi.nlm.nih.gov/pubmed/34926946
http://dx.doi.org/10.1021/acsomega.1c05321