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Evaluating the stability of opioid efficacy over 12 months in patients with chronic noncancer pain who initially demonstrate benefit from extended release oxycodone or hydrocodone: harmonization of Food and Drug Administration patient-level drug safety study data

Opioids relieve acute pain, but there is little evidence to support the stability of the benefit over long-term treatment of chronic noncancer pain. Previous systematic reviews consider only group level published data which did not provide adequate detail. Our goal was to use patient-level data to e...

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Detalles Bibliográficos
Autores principales: Farrar, John T., Bilker, Warren B., Cochetti, Philip T., Argoff, Charles E., Haythornthwaite, Jennifer, Katz, Nathaniel P., Gilron, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675053/
https://www.ncbi.nlm.nih.gov/pubmed/34261978
http://dx.doi.org/10.1097/j.pain.0000000000002331