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Visualizing the Potential Impairment of Polymyxin B to Central Nervous System Through MR Susceptibility-Weighted Imaging

Polymyxin B (PMB) exert bactericidal effects on the cell wall of Gram-negative bacteria, leading to changes in the permeability of the cytoplasmic membrane and resulting in cell death, which is sensitive to the multi-resistant Gram-negative bacteria. However, the severe toxicity and adverse side eff...

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Detalles Bibliográficos
Autores principales: Zhang, Ni, Zhu, Lichong, Ouyang, Qiuhong, Yue, Saisai, Huang, Yichun, Qu, Shuang, Li, Runwei, Qiao, Yuanyuan, Xu, Man, He, Fangfei, Zhao, Bin, Wei, Lai, Wu, Xiaoai, Zhang, Peisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675099/
https://www.ncbi.nlm.nih.gov/pubmed/34925041
http://dx.doi.org/10.3389/fphar.2021.784864