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HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells

The autophagy-lysosomal pathway is an essential cellular mechanism that degrades aggregated proteins and damaged cellular components to maintain cellular homeostasis. Here, we identified HEXA-018, a novel compound containing a catechol derivative structure, as a novel inducer of autophagy. HEXA-018...

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Detalles Bibliográficos
Autores principales:	Lee, Shinrye, Jo, Myungjin, Lee, Hye Eun, Jeon, Yu-Mi, Kim, Seyeon, Kwon, Younghwi, Woo, Junghwa, Han, Shin, Mun, Ji Young, Kim, Hyung-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675103/ https://www.ncbi.nlm.nih.gov/pubmed/34925009 http://dx.doi.org/10.3389/fphar.2021.747975

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