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Plasmin drives burn-induced systemic inflammatory response syndrome

Severe injuries, such as burns, provoke a systemic inflammatory response syndrome (SIRS) that imposes pathology on all organs. Simultaneously, severe injury also elicits activation of the fibrinolytic protease plasmin. While the principal adverse outcome of plasmin activation in severe injury is com...

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Detalles Bibliográficos
Autores principales: Gibson, Breanne H. Y., Wollenman, Colby C., Moore-Lotridge, Stephanie N., Keller, Patrick R., Summitt, J. Blair, Revenko, Alexey R., Flick, Matthew J., Blackwell, Timothy S., Schoenecker, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675186/
https://www.ncbi.nlm.nih.gov/pubmed/34877937
http://dx.doi.org/10.1172/jci.insight.154439