Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells

Leukemia stem cells (LSCs) promote the disease and seem resistant to therapy and immune control. Why LSCs are selectively resistant against elimination by CD8(+) cytotoxic T cells (CTLs) is still unknown. In this study, we demonstrate that LSCs in chronic myeloid leukemia (CML) can be recognized and...

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Detalles Bibliográficos
Autores principales: Hinterbrandner, Magdalena, Rubino, Viviana, Stoll, Carina, Forster, Stefan, Schnüriger, Noah, Radpour, Ramin, Baerlocher, Gabriela M., Ochsenbein, Adrian F., Riether, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675189/
https://www.ncbi.nlm.nih.gov/pubmed/34727093
http://dx.doi.org/10.1172/jci.insight.151797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675189/
https://www.ncbi.nlm.nih.gov/pubmed/34727093
http://dx.doi.org/10.1172/jci.insight.151797

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