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Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells
Leukemia stem cells (LSCs) promote the disease and seem resistant to therapy and immune control. Why LSCs are selectively resistant against elimination by CD8(+) cytotoxic T cells (CTLs) is still unknown. In this study, we demonstrate that LSCs in chronic myeloid leukemia (CML) can be recognized and...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675189/ https://www.ncbi.nlm.nih.gov/pubmed/34727093 http://dx.doi.org/10.1172/jci.insight.151797 |