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Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART

Understanding viral rebound in pediatric HIV-1 infection may inform the development of alternatives to lifelong antiretroviral therapy (ART) to achieve viral remission. We thus investigated viral rebound after analytical treatment interruption (ATI) in 10 infant macaques orally infected with SHIV.C....

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Detalles Bibliográficos
Autores principales: Obregon-Perko, Veronica, Bricker, Katherine M., Mensah, Gloria, Uddin, Ferzan, Rotolo, Laura, Vanover, Daryll, Desai, Yesha, Santangelo, Philip J., Jean, Sherrie, Wood, Jennifer S., Connor-Stroud, Fawn C., Ehnert, Stephanie, Berendam, Stella J., Liang, Shan, Vanderford, Thomas H., Bar, Katharine J., Shaw, George M., Silvestri, Guido, Kumar, Amit, Fouda, Genevieve G., Permar, Sallie R., Chahroudi, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675190/
https://www.ncbi.nlm.nih.gov/pubmed/34699383
http://dx.doi.org/10.1172/jci.insight.152526