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Increased long noncoding RNA LINK-A contributes to rheumatoid synovial inflammation and aggression

Fibroblast-like synoviocytes (FLSs) play a key role in controlling synovial inflammation and joint destruction in rheumatoid arthritis (RA). The contribution of long noncoding RNAs (lncRNAs) to RA is largely unknown. Here, we show that the lncRNA LINK-A, located mainly in cytoplasm, has higher-than-...

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Detalles Bibliográficos
Autores principales: Wang, Jingnan, Shen, Chuyu, Li, Ruiru, Wang, Cuicui, Xiao, Youjun, Kuang, Yu, Lao, Minxi, Xu, Siqi, Shi, Maohua, Cai, Xiaoyan, Liang, Liuqin, Xu, Hanshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675191/
https://www.ncbi.nlm.nih.gov/pubmed/34877935
http://dx.doi.org/10.1172/jci.insight.146757