Cargando…
Increased long noncoding RNA LINK-A contributes to rheumatoid synovial inflammation and aggression
Fibroblast-like synoviocytes (FLSs) play a key role in controlling synovial inflammation and joint destruction in rheumatoid arthritis (RA). The contribution of long noncoding RNAs (lncRNAs) to RA is largely unknown. Here, we show that the lncRNA LINK-A, located mainly in cytoplasm, has higher-than-...
Autores principales: | Wang, Jingnan, Shen, Chuyu, Li, Ruiru, Wang, Cuicui, Xiao, Youjun, Kuang, Yu, Lao, Minxi, Xu, Siqi, Shi, Maohua, Cai, Xiaoyan, Liang, Liuqin, Xu, Hanshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675191/ https://www.ncbi.nlm.nih.gov/pubmed/34877935 http://dx.doi.org/10.1172/jci.insight.146757 |
Ejemplares similares
-
cGAS/STING signaling in the regulation of rheumatoid synovial aggression
por: Li, Ruiru, et al.
Publicado: (2022) -
SMOC2 promotes aggressive behavior of fibroblast-like synoviocytes in rheumatoid arthritis through transcriptional and post-transcriptional regulating MYO1C
por: Liu, Di, et al.
Publicado: (2022) -
Increased SUMO-activating enzyme SAE1/UBA2 promotes glycolysis and pathogenic behavior of rheumatoid fibroblast-like synoviocytes
por: Wang, Cuicui, et al.
Publicado: (2020) -
Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation via Blocking AMP-Activated Protein Kinase Activation
por: Shi, Maohua, et al.
Publicado: (2018) -
Myricitrin inhibits fibroblast-like synoviocyte-mediated rheumatoid synovial inflammation and joint destruction by targeting AIM2
por: Shen, Chuyu, et al.
Publicado: (2022)