TTP protects against acute liver failure by regulating CCL2 and CCL5 through m(6)A RNA methylation

Tristetraprolin (TTP), an important immunosuppressive protein regulating mRNA decay through recognition of the AU-rich elements (AREs) within the 3′-UTRs of mRNAs, participates in the pathogenesis of liver diseases. However, whether TTP regulates mRNA stability through other mechanisms remains poorl...

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Detalles Bibliográficos
Autores principales: Xiao, Pingping, Li, Mingxuan, Zhou, Mengsi, Zhao, Xuejun, Wang, Cheng, Qiu, Jinglin, Fang, Qian, Jiang, Hong, Dong, Huifen, Zhou, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675193/
https://www.ncbi.nlm.nih.gov/pubmed/34877932
http://dx.doi.org/10.1172/jci.insight.149276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675193/
https://www.ncbi.nlm.nih.gov/pubmed/34877932
http://dx.doi.org/10.1172/jci.insight.149276

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