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TTP protects against acute liver failure by regulating CCL2 and CCL5 through m(6)A RNA methylation

Tristetraprolin (TTP), an important immunosuppressive protein regulating mRNA decay through recognition of the AU-rich elements (AREs) within the 3′-UTRs of mRNAs, participates in the pathogenesis of liver diseases. However, whether TTP regulates mRNA stability through other mechanisms remains poorl...

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Detalles Bibliográficos
Autores principales:	Xiao, Pingping, Li, Mingxuan, Zhou, Mengsi, Zhao, Xuejun, Wang, Cheng, Qiu, Jinglin, Fang, Qian, Jiang, Hong, Dong, Huifen, Zhou, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675193/ https://www.ncbi.nlm.nih.gov/pubmed/34877932 http://dx.doi.org/10.1172/jci.insight.149276

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