ARPC1B binds WASP to control actin polymerization and curtail tonic signaling in B cells

Immune cells exhibit low-level, constitutive signaling at rest (tonic signaling). Such tonic signals are required for fundamental processes, including the survival of B lymphocytes, but when they are elevated by genetic or environmental causes, they can lead to autoimmunity. Events that control ongo...

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Detalles Bibliográficos
Autores principales: Leung, Gabriella, Zhou, Yuhuan, Ostrowski, Philip, Mylvaganam, Sivakami, Boroumand, Parastoo, Mulder, Daniel J., Guo, Conghui, Muise, Aleixo M., Freeman, Spencer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675194/
https://www.ncbi.nlm.nih.gov/pubmed/34673575
http://dx.doi.org/10.1172/jci.insight.149376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675194/
https://www.ncbi.nlm.nih.gov/pubmed/34673575
http://dx.doi.org/10.1172/jci.insight.149376

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