VEGFR2 activity on myeloid cells mediates immune suppression in the tumor microenvironment

Angiogenesis, a hallmark of cancer, is induced by vascular endothelial growth factor–A (hereafter VEGF). As a result, anti-VEGF therapy is commonly used for cancer treatment. Recent studies have found that VEGF expression is also associated with immune suppression in patients with cancer. This conne...

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Detalles Bibliográficos
Autores principales: Zhang, Yuqing, Huang, Huocong, Coleman, Morgan, Ziemys, Arturas, Gopal, Purva, Kazmi, Syed M., Brekken, Rolf A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675197/
https://www.ncbi.nlm.nih.gov/pubmed/34673569
http://dx.doi.org/10.1172/jci.insight.150735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675197/
https://www.ncbi.nlm.nih.gov/pubmed/34673569
http://dx.doi.org/10.1172/jci.insight.150735

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