Targeting senescence-like fibroblasts radiosensitizes non–small cell lung cancer and reduces radiation-induced pulmonary fibrosis

Cancer cell radioresistance is the primary cause of the decreased curability of non–small cell lung cancer (NSCLC) observed in patients receiving definitive radiotherapy (RT). Following RT, a set of microenvironmental stress responses is triggered, including cell senescence. However, cell senescence...

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Detalles Bibliográficos
Autores principales: Meng, Jingshu, Li, Yan, Wan, Chao, Sun, Yajie, Dai, Xiaomeng, Huang, Jing, Hu, Yan, Gao, Yanan, Wu, Bian, Zhang, Zhanjie, Jiang, Ke, Xu, Shuangbing, Lovell, Jonathan F., Hu, Yu, Wu, Gang, Jin, Honglin, Yang, Kunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675198/
https://www.ncbi.nlm.nih.gov/pubmed/34877934
http://dx.doi.org/10.1172/jci.insight.146334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675198/
https://www.ncbi.nlm.nih.gov/pubmed/34877934
http://dx.doi.org/10.1172/jci.insight.146334

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