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Weak multivalent biomolecular interactions: a strength versus numbers tug of war with implications for phase partitioning

In this short Perspective, we discuss how recent dynamic live-cell imaging experiments have challenged our understanding of mechanisms driving functional molecular interactions in vivo. While we have generally considered the formation of functional biomolecular complexes as resulting from the stable...

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Detalles Bibliográficos
Autores principales: Darzacq, Xavier, Tjian, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675282/
https://www.ncbi.nlm.nih.gov/pubmed/34772790
http://dx.doi.org/10.1261/rna.079004.121