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What are the distinguishing features and size requirements of biomolecular condensates and their implications for RNA-containing condensates?

Exciting recent work has highlighted that numerous cellular compartments lack encapsulating lipid bilayers (often called “membraneless organelles”), and that their structure and function are central to the regulation of key biological processes, including transcription, RNA splicing, translation, an...

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Detalles Bibliográficos
Autores principales: Forman-Kay, Julie D., Ditlev, Jonathon A., Nosella, Michael L., Lee, Hyun O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675286/
https://www.ncbi.nlm.nih.gov/pubmed/34772786
http://dx.doi.org/10.1261/rna.079026.121