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Inhibition of DRP1 Impedes Zygotic Genome Activation and Preimplantation Development in Mice

Mitochondrion plays an indispensable role during preimplantation embryo development. Dynamic-related protein 1 (DRP1) is critical for mitochondrial fission and controls oocyte maturation. However, its role in preimplantation embryo development is still lacking. In this study, we demonstrate that inh...

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Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Mei, Ning-Hua, Cheng, Gui-Ping, Yang, Jing, Zhou, Li-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675387/
https://www.ncbi.nlm.nih.gov/pubmed/34926466
http://dx.doi.org/10.3389/fcell.2021.788512