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P-tau and neurodegeneration mediate the effect of β-amyloid on cognition in non-demented elders

BACKGROUND: There are many pathological changes in the brains of Alzheimer’s disease (AD) patients. For many years, the mainstream view on the pathogenesis of AD believes that β-amyloid (Aβ) usually acts independently in addition to triggering functions. However, the evidence now accumulating indica...

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Detalles Bibliográficos
Autores principales: Ma, Ling-Zhi, Hu, Hao, Wang, Zuo-Teng, Ou, Ya-Nan, Dong, Qiang, Tan, Lan, Yu, Jin-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675473/
https://www.ncbi.nlm.nih.gov/pubmed/34911582
http://dx.doi.org/10.1186/s13195-021-00943-z