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Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress

BACKGROUND: Tissue hypoxia is a key feature of several endemic hepatic diseases, including alcoholic and non-alcoholic fatty liver disease, and organ failure. Hypoxia imposes a severe metabolic challenge on the liver, potentially disrupting its capacity to carry out essential functions including fue...

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Detalles Bibliográficos
Autores principales: O’Brien, Katie A., McNally, Ben D., Sowton, Alice P., Murgia, Antonio, Armitage, James, Thomas, Luke W., Krause, Fynn N., Maddalena, Lucas A., Francis, Ian, Kavanagh, Stefan, Williams, Dominic P., Ashcroft, Margaret, Griffin, Julian L., Lyon, Jonathan J., Murray, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675474/
https://www.ncbi.nlm.nih.gov/pubmed/34911556
http://dx.doi.org/10.1186/s12915-021-01192-0