JNK signaling provides a novel therapeutic target for Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a monogenic X-linked neurodevelopmental disorder characterized by loss-of-function mutations in the MECP2 gene, which lead to structural and functional changes in synapse communication, and impairments of neural activity at the basis of cognitive deficits that prog...

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Detalles Bibliográficos
Autores principales: Musi, Clara Alice, Castaldo, Anna Maria, Valsecchi, Anna Elisa, Cimini, Sara, Morello, Noemi, Pizzo, Riccardo, Renieri, Alessandra, Meloni, Ilaria, Bonati, Maurizio, Giustetto, Maurizio, Borsello, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675514/
https://www.ncbi.nlm.nih.gov/pubmed/34911542
http://dx.doi.org/10.1186/s12915-021-01190-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675514/
https://www.ncbi.nlm.nih.gov/pubmed/34911542
http://dx.doi.org/10.1186/s12915-021-01190-2

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