Liposome nano‐formulation with cationic polar lipid DOTAP and cholesterol as a suitable pH‐responsive carrier for molecular therapeutic drug (all‐trans retinoic acid) delivery to lung cancer cells

The molecular targeted drug ATRA demands a suitable carrier that delivers to the cancer site due to its poor bioavailability and drug resistance. ATRA, being a lipid with carboxylic acid, has been nano‐formulated as a cationic lipo‐ATRA with DOTAP:cholesterol:ATRA (5:4:1) and its pH‐responsive relea...

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Detalles Bibliográficos
Autores principales: Grace, Viswanathan Mariammal Berlin, Wilson, Devarajan David, Guruvayoorappan, Chandrasekharan, Danisha, Jesubatham Perinba, Bonati, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675848/
https://www.ncbi.nlm.nih.gov/pubmed/34694713
http://dx.doi.org/10.1049/nbt2.12028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675848/
https://www.ncbi.nlm.nih.gov/pubmed/34694713
http://dx.doi.org/10.1049/nbt2.12028

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