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Oral Efficacy of a Diselenide Compound Loaded in Nanostructured Lipid Carriers in a Murine Model of Visceral Leishmaniasis

[Image: see text] Leishmaniasis urgently needs new oral treatments, as it is one of the most important neglected tropical diseases that affects people with poor resources. The drug discovery pipeline for oral administration currently discards entities with poor aqueous solubility and permeability (c...

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Detalles Bibliográficos
Autores principales: Etxebeste-Mitxeltorena, Mikel, Moreno, Esther, Carvalheiro, Manuela, Calvo, Alba, Navarro-Blasco, Iñigo, González-Peñas, Elena, Álvarez-Galindo, José I., Plano, Daniel, Irache, Juan M., Almeida, Antonio J., Sanmartín, Carmen, Espuelas, Socorro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675869/
https://www.ncbi.nlm.nih.gov/pubmed/34767359
http://dx.doi.org/10.1021/acsinfecdis.1c00394