Transcriptomic Changes Highly Similar to Alzheimer’s Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging

Aging is a major risk factor for late-onset Alzheimer’s disease (LOAD). How aging contributes to the development of LOAD remains elusive. In this study, we examined multiple large-scale transcriptomic datasets from both normal aging and LOAD brains to understand the molecular interconnection between...

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Detalles Bibliográficos
Autores principales: Peng, Shouneng, Zeng, Lu, Haure-Mirande, Jean-Vianney, Wang, Minghui, Huffman, Derek M., Haroutunian, Vahram, Ehrlich, Michelle E., Zhang, Bin, Tu, Zhidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675870/
https://www.ncbi.nlm.nih.gov/pubmed/34924992
http://dx.doi.org/10.3389/fnagi.2021.711524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675870/
https://www.ncbi.nlm.nih.gov/pubmed/34924992
http://dx.doi.org/10.3389/fnagi.2021.711524

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