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Stable Gold-Nanoparticle-Based Vaccine for the Targeted Delivery of Tumor-Associated Glycopeptide Antigens

[Image: see text] We have developed a novel antigen delivery system based on polysaccharide-coated gold nanoparticles (AuNPs) targeted to antigen-presenting cells (APCs) expressing Dectin-1. AuNPs were synthesized de novo using yeast-derived β-1,3-glucans (B13G) as the reductant and passivating agen...

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Detalles Bibliográficos
Autores principales: Trabbic, Kevin R., Kleski, Kristopher A., Barchi, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675876/
https://www.ncbi.nlm.nih.gov/pubmed/34927166
http://dx.doi.org/10.1021/acsbiomedchemau.1c00021