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Molecular Investigation of Chicken Acid-Sensing Ion Channel 1 β11-12 Linker Isomerization and Channel Kinetics

Structures of the trimeric acid-sensing ion channel have been solved in the resting, toxin-bound open and desensitized states. Within the extracellular domain, there is little difference between the toxin-bound open state and the desensitized state. The main exception is that a loop connecting the 1...

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Detalles Bibliográficos
Autores principales: Rook, Matthew L., Ananchenko, Anna, Musgaard, Maria, MacLean, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675884/
https://www.ncbi.nlm.nih.gov/pubmed/34924957
http://dx.doi.org/10.3389/fncel.2021.761813