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Molecular Investigation of Chicken Acid-Sensing Ion Channel 1 β11-12 Linker Isomerization and Channel Kinetics
Structures of the trimeric acid-sensing ion channel have been solved in the resting, toxin-bound open and desensitized states. Within the extracellular domain, there is little difference between the toxin-bound open state and the desensitized state. The main exception is that a loop connecting the 1...
Autores principales: | Rook, Matthew L., Ananchenko, Anna, Musgaard, Maria, MacLean, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675884/ https://www.ncbi.nlm.nih.gov/pubmed/34924957 http://dx.doi.org/10.3389/fncel.2021.761813 |
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