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Neural Stem Cells Overexpressing Nerve Growth Factor Improve Functional Recovery in Rats Following Spinal Cord Injury via Modulating Microenvironment and Enhancing Endogenous Neurogenesis

Spinal cord injury (SCI) is a devastating event characterized by severe motor, sensory, and autonomic dysfunction. Currently, there is no effective treatment. Previous studies showed neural growth factor (NGF) administration was a potential treatment for SCI. However, its targeted delivery is still...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Gu, Sujie, Gan, Jinlu, Tian, Yi, Zhang, Fangcheng, Zhao, Hongyang, Lei, Deqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675903/
https://www.ncbi.nlm.nih.gov/pubmed/34924958
http://dx.doi.org/10.3389/fncel.2021.773375