Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans

Changes in histone post-translational modifications are associated with aging through poorly defined mechanisms. Histone 3 lysine 4 (H3K4) methylation at promoters is deposited by SET1 family methyltransferases acting within conserved multiprotein complexes known as COMPASS. Previous work yielded co...

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Detalles Bibliográficos
Autores principales: Caron, Matthieu, Gely, Loïc, Garvis, Steven, Adrait, Annie, Couté, Yohann, Palladino, Francesca, Fabrizio, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675910/
https://www.ncbi.nlm.nih.gov/pubmed/34893559
http://dx.doi.org/10.26508/lsa.202101140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675910/
https://www.ncbi.nlm.nih.gov/pubmed/34893559
http://dx.doi.org/10.26508/lsa.202101140

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