Bis-choline tetrathiomolybdate prevents copper-induced blood–brain barrier damage

In Wilson disease, excessive copper accumulates in patients’ livers and may, upon serum leakage, severely affect the brain according to current viewpoints. Present remedies aim at avoiding copper toxicity by chelation, for example, by D-penicillamine (DPA) or bis-choline tetrathiomolybdate (ALXN1840...

Descripción completa

Detalles Bibliográficos
Autores principales: Borchard, Sabine, Raschke, Stefanie, Zak, Krzysztof M, Eberhagen, Carola, Einer, Claudia, Weber, Elisabeth, Müller, Sandra M, Michalke, Bernhard, Lichtmannegger, Josef, Wieser, Albrecht, Rieder, Tamara, Popowicz, Grzegorz M, Adamski, Jerzy, Klingenspor, Martin, Coles, Andrew H, Viana, Ruth, Vendelbo, Mikkel H, Sandahl, Thomas D, Schwerdtle, Tanja, Plitz, Thomas, Zischka, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675913/
https://www.ncbi.nlm.nih.gov/pubmed/34857647
http://dx.doi.org/10.26508/lsa.202101164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675913/
https://www.ncbi.nlm.nih.gov/pubmed/34857647
http://dx.doi.org/10.26508/lsa.202101164

Ejemplares similares