Cargando…
Bis-choline tetrathiomolybdate prevents copper-induced blood–brain barrier damage
In Wilson disease, excessive copper accumulates in patients’ livers and may, upon serum leakage, severely affect the brain according to current viewpoints. Present remedies aim at avoiding copper toxicity by chelation, for example, by D-penicillamine (DPA) or bis-choline tetrathiomolybdate (ALXN1840...
Autores principales: | Borchard, Sabine, Raschke, Stefanie, Zak, Krzysztof M, Eberhagen, Carola, Einer, Claudia, Weber, Elisabeth, Müller, Sandra M, Michalke, Bernhard, Lichtmannegger, Josef, Wieser, Albrecht, Rieder, Tamara, Popowicz, Grzegorz M, Adamski, Jerzy, Klingenspor, Martin, Coles, Andrew H, Viana, Ruth, Vendelbo, Mikkel H, Sandahl, Thomas D, Schwerdtle, Tanja, Plitz, Thomas, Zischka, Hans |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675913/ https://www.ncbi.nlm.nih.gov/pubmed/34857647 http://dx.doi.org/10.26508/lsa.202101164 |
Ejemplares similares
-
Bis‐choline Tetrathiomolybdate as Old Drug in a New Design for Wilson’s Disease: Good for Brain and Liver?
por: Stremmel, Wolfgang
Publicado: (2018) -
Analyzing the Therapeutic Efficacy of Bis-Choline-Tetrathiomolybdate in the Atp7b(−/−) Copper Overload Mouse Model
por: Kim, Philipp, et al.
Publicado: (2021) -
A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats
por: Einer, Claudia, et al.
Publicado: (2018) -
Ammonium tetrathiomolybdate treatment of copper‐associated hepatopathy in dogs
por: Langlois, Daniel K., et al.
Publicado: (2019) -
Mitochondrial Impairment by MitoBloCK-6 Inhibits Liver Cancer Cell Proliferation
por: Kabiri, Yaschar, et al.
Publicado: (2021)