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A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis

Influenza virus infection is dependent on host cellular factors, and identification of these factors and their underlying mechanisms can provide important information for the development of strategies to inhibit viral infection. Here, we used a highly pathogenic H5N1 influenza virus to perform a gen...

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Detalles Bibliográficos
Autores principales: Song, Yangming, Huang, Haixiang, Hu, Yuzhen, Zhang, Jiwen, Li, Fang, Yin, Xin, Shi, Jianzhong, Li, Yanbing, Li, Chengjun, Zhao, Dongming, Chen, Hualan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675923/
https://www.ncbi.nlm.nih.gov/pubmed/34871331
http://dx.doi.org/10.1371/journal.ppat.1010141