In silico identification of potential calcium dynamics and sarcomere targets for recovering left ventricular function in rat heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) is a complex disease associated with multiple co-morbidities, where impaired cardiac mechanics are often the end effect. At the cellular level, cardiac mechanics can be pharmacologically manipulated by altering calcium signalling and the sarcome...

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Detalles Bibliográficos
Autores principales: Longobardi, Stefano, Sher, Anna, Niederer, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675924/
https://www.ncbi.nlm.nih.gov/pubmed/34871310
http://dx.doi.org/10.1371/journal.pcbi.1009646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675924/
https://www.ncbi.nlm.nih.gov/pubmed/34871310
http://dx.doi.org/10.1371/journal.pcbi.1009646

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